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Falsification of the instrumental variable conditions in Mendelian randomization studies in the UK Biobank

Mendelian randomization (MR) is an increasingly popular approach to estimating causal effects. Although the assumptions underlying MR cannot be verified, they imply certain constraints, the instrumental inequalities, which can be used to falsify the MR conditions. However, the instrumental inequalit...

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Detalles Bibliográficos
Autores principales: Guo, Kelly, Diemer, Elizabeth W., Labrecque, Jeremy A., Swanson, Sonja A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501946/
https://www.ncbi.nlm.nih.gov/pubmed/37253997
http://dx.doi.org/10.1007/s10654-023-01003-6