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How Pol α-primase is targeted to replisomes to prime eukaryotic DNA replication
During eukaryotic DNA replication, Pol α-primase generates primers at replication origins to start leading-strand synthesis and every few hundred nucleotides during discontinuous lagging-strand replication. How Pol α-primase is targeted to replication forks to prime DNA synthesis is not fully unders...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501992/ https://www.ncbi.nlm.nih.gov/pubmed/37506699 http://dx.doi.org/10.1016/j.molcel.2023.06.035 |