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Speg interactions that regulate the stability of excitation-contraction coupling protein complexes in triads and dyads

Here we show that striated muscle preferentially expressed protein kinase α (Spegα) maintains cardiac function in hearts with Spegβ deficiency. Speg is required for stability of excitation-contraction coupling (ECC) complexes and interacts with esterase D (Esd), Cardiomyopathy-Associated Protein 5 (...

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Detalles Bibliográficos
Autores principales: Lee, Chang Seok, Jung, Sung Yun, Yee, Rachel Sue Zhen, Agha, Nadia H., Hong, Jin, Chang, Ting, Babcock, Lyle W., Fleischman, Jorie D., Clayton, Benjamin, Hanna, Amy D., Ward, Christopher S., Lanza, Denise, Hurley, Ayrea E., Zhang, Pumin, Wehrens, Xander H. T., Lagor, William R., Rodney, George G., Hamilton, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502019/
https://www.ncbi.nlm.nih.gov/pubmed/37709832
http://dx.doi.org/10.1038/s42003-023-05330-y