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The structure of a Plasmodium vivax Tryptophan Rich Antigen domain suggests a lipid binding function for a pan-Plasmodium multi-gene family

Tryptophan Rich Antigens (TRAgs) are encoded by a multi-gene family found in all Plasmodium species, but are significantly expanded in P. vivax and closely related parasites. We show that multiple P. vivax TRAgs are expressed on the merozoite surface and that one, PVP01_0000100 binds red blood cells...

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Detalles Bibliográficos
Autores principales: Kundu, Prasun, Naskar, Deboki, McKie, Shannon J., Dass, Sheena, Kanjee, Usheer, Introini, Viola, Ferreira, Marcelo U., Cicuta, Pietro, Duraisingh, Manoj, Deane, Janet E., Rayner, Julian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502043/
https://www.ncbi.nlm.nih.gov/pubmed/37709739
http://dx.doi.org/10.1038/s41467-023-40885-8