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Topological data analysis of spatial patterning in heterogeneous cell populations: clustering and sorting with varying cell-cell adhesion

Different cell types aggregate and sort into hierarchical architectures during the formation of animal tissues. The resulting spatial organization depends (in part) on the strength of adhesion of one cell type to itself relative to other cell types. However, automated and unsupervised classification...

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Detalles Bibliográficos
Autores principales: Bhaskar, Dhananjay, Zhang, William Y., Volkening, Alexandria, Sandstede, Björn, Wong, Ian Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502054/
https://www.ncbi.nlm.nih.gov/pubmed/37709793
http://dx.doi.org/10.1038/s41540-023-00302-8