MDIG-mediated H3K9me3 demethylation upregulates Myc by activating OTX2 and facilitates liver regeneration

The mineral dust-induced gene (MDIG) comprises a conserved JmjC domain and has the ability to demethylate histone H3 lysine 9 trimethylation (H3K9me3). Previous studies have indicated the significance of MDIG in promoting cell proliferation by modulating cell-cycle transition. However, its involveme...

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Detalles Bibliográficos
Autores principales: Du, Jinpeng, Liao, Wenwei, Wang, Haichuan, Hou, Guimin, Liao, Min, Xu, Lin, Huang, Jiwei, Yuan, Kefei, Chen, Xiangzheng, Zeng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502063/
https://www.ncbi.nlm.nih.gov/pubmed/37709738
http://dx.doi.org/10.1038/s41392-023-01575-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502063/
https://www.ncbi.nlm.nih.gov/pubmed/37709738
http://dx.doi.org/10.1038/s41392-023-01575-5

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