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Activator-blocker model of transcriptional regulation by pioneer-like factors

Zygotic genome activation (ZGA) in the development of flies, fish, frogs and mammals depends on pioneer-like transcription factors (TFs). Those TFs create open chromatin regions, promote histone acetylation on enhancers, and activate transcription. Here, we use the panel of single, double and triple...

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Detalles Bibliográficos
Autores principales: Riesle, Aileen Julia, Gao, Meijiang, Rosenblatt, Marcus, Hermes, Jacques, Hass, Helge, Gebhard, Anna, Veil, Marina, Grüning, Björn, Timmer, Jens, Onichtchouk, Daria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502082/
https://www.ncbi.nlm.nih.gov/pubmed/37709752
http://dx.doi.org/10.1038/s41467-023-41507-z