PEGylated thrombopoietin mimetic, JNJ‑26366821 a novel prophylactic radiation countermeasure for acute radiation injury

Thrombopoietin (TPO) is the primary regulator of platelet generation and a stimulator of multilineage hematopoietic recovery following exposure to total body irradiation (TBI). JNJ‑26366821, a novel PEGylated TPO mimetic peptide, stimulates platelet production without developing neutralizing antibod...

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Detalles Bibliográficos
Autores principales: Holmes-Hampton, Gregory P., Kumar, Vidya P., Biswas, Shukla, Stone, Sasha, Sharma, Neel K., Legesse, Betre, Vercellino, Justin, Guha, Chandan, Eichenbaum, Gary, Ghosh, Sanchita P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502090/
https://www.ncbi.nlm.nih.gov/pubmed/37709916
http://dx.doi.org/10.1038/s41598-023-42443-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502090/
https://www.ncbi.nlm.nih.gov/pubmed/37709916
http://dx.doi.org/10.1038/s41598-023-42443-0

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