Endoplasmic reticulum stress: molecular mechanism and therapeutic targets

The endoplasmic reticulum (ER) functions as a quality-control organelle for protein homeostasis, or “proteostasis”. The protein quality control systems involve ER-associated degradation, protein chaperons, and autophagy. ER stress is activated when proteostasis is broken with an accumulation of misf...

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Detalles Bibliográficos
Autores principales: Chen, Xingyi, Shi, Chaoran, He, Meihui, Xiong, Siqi, Xia, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502142/
https://www.ncbi.nlm.nih.gov/pubmed/37709773
http://dx.doi.org/10.1038/s41392-023-01570-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502142/
https://www.ncbi.nlm.nih.gov/pubmed/37709773
http://dx.doi.org/10.1038/s41392-023-01570-w

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