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Discovery of an orally effective double-stapled peptide for reducing ovariectomy-induced bone loss in mice
Stapled peptides with significantly enhanced pharmacological profiles have emerged as promising therapeutic molecules due to their remarkable resistance to proteolysis and performance to penetrate cells. The all-hydrocarbon peptide stapling technique has already widely adopted with great success, yi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502273/ https://www.ncbi.nlm.nih.gov/pubmed/37719364 http://dx.doi.org/10.1016/j.apsb.2023.05.004 |