Discovery of an orally effective double-stapled peptide for reducing ovariectomy-induced bone loss in mice

Stapled peptides with significantly enhanced pharmacological profiles have emerged as promising therapeutic molecules due to their remarkable resistance to proteolysis and performance to penetrate cells. The all-hydrocarbon peptide stapling technique has already widely adopted with great success, yi...

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Detalles Bibliográficos
Autores principales: Cong, Wei, Shen, Huaxing, Liao, Xiufei, Zheng, Mengjun, Kong, Xianglong, Wang, Zhe, Chen, Si, Li, Yulei, Hu, Honggang, Li, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502273/
https://www.ncbi.nlm.nih.gov/pubmed/37719364
http://dx.doi.org/10.1016/j.apsb.2023.05.004

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