Lethal adulthood myelin breakdown by oligodendrocyte-specific Ddx54 knockout

Multiple sclerosis (MS) is a leading disease that causes disability in young adults. We have previously shown that a DEAD-box RNA helicase Ddx54 binds to mRNA and protein isoforms of myelin basic protein (MBP) and that Ddx54 siRNA blocking abrogates oligodendrocyte migration and myelination. Herein,...

Descripción completa

Detalles Bibliográficos
Autores principales: Oizumi, Hiroaki, Miyamoto, Yuki, Seiwa, Chika, Yamamoto, Masahiro, Yoshioka, Nozomu, Iizuka, Seiichi, Torii, Tomohiro, Ohbuchi, Katsuya, Mizoguchi, Kazushige, Yamauchi, Junji, Asou, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502337/
https://www.ncbi.nlm.nih.gov/pubmed/37720086
http://dx.doi.org/10.1016/j.isci.2023.107448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502337/
https://www.ncbi.nlm.nih.gov/pubmed/37720086
http://dx.doi.org/10.1016/j.isci.2023.107448

Ejemplares similares