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Lethal adulthood myelin breakdown by oligodendrocyte-specific Ddx54 knockout

Multiple sclerosis (MS) is a leading disease that causes disability in young adults. We have previously shown that a DEAD-box RNA helicase Ddx54 binds to mRNA and protein isoforms of myelin basic protein (MBP) and that Ddx54 siRNA blocking abrogates oligodendrocyte migration and myelination. Herein,...

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Detalles Bibliográficos
Autores principales:	Oizumi, Hiroaki, Miyamoto, Yuki, Seiwa, Chika, Yamamoto, Masahiro, Yoshioka, Nozomu, Iizuka, Seiichi, Torii, Tomohiro, Ohbuchi, Katsuya, Mizoguchi, Kazushige, Yamauchi, Junji, Asou, Hiroaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502337/ https://www.ncbi.nlm.nih.gov/pubmed/37720086 http://dx.doi.org/10.1016/j.isci.2023.107448

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