αβ-T cell receptor transduction gives superior mitochondrial function to γδ-T cells with promising persistence

Adoptive cell therapy using allogeneic γδ-T cells is a promising option for off-the-shelf T cell products with a low risk of graft-versus-host disease (GVHD). Long-term persistence may boost the clinical development of γδ-T cell products. In this study, we found that genetically modified Vγ9(+)Vδ2(+...

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Detalles Bibliográficos
Autores principales: Ishihara, Mikiya, Miwa, Hiroshi, Fujiwara, Hiroshi, Akahori, Yasushi, Kato, Takuma, Tanaka, Yoshimasa, Tawara, Isao, Shiku, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502403/
https://www.ncbi.nlm.nih.gov/pubmed/37720098
http://dx.doi.org/10.1016/j.isci.2023.107802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502403/
https://www.ncbi.nlm.nih.gov/pubmed/37720098
http://dx.doi.org/10.1016/j.isci.2023.107802

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