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αβ-T cell receptor transduction gives superior mitochondrial function to γδ-T cells with promising persistence
Adoptive cell therapy using allogeneic γδ-T cells is a promising option for off-the-shelf T cell products with a low risk of graft-versus-host disease (GVHD). Long-term persistence may boost the clinical development of γδ-T cell products. In this study, we found that genetically modified Vγ9(+)Vδ2(+...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502403/ https://www.ncbi.nlm.nih.gov/pubmed/37720098 http://dx.doi.org/10.1016/j.isci.2023.107802 |