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Mobilization-based engraftment of haematopoietic stem cells: a new perspective for chemotherapy-free gene therapy and transplantation

INTRODUCTION: In haematopoietic stem cell transplantation (HSCT), haematopoietic stem cells (HSCs) from a healthy donor replace the patient’s ones. Ex vivo HSC gene therapy (HSC-GT) is a form of HSCT in which HSCs, usually from an autologous source, are genetically modified before infusion, to gener...

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Detalles Bibliográficos
Autores principales: Canarutto, Daniele, Omer Javed, Attya, Pedrazzani, Gabriele, Ferrari, Samuele, Naldini, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502445/
https://www.ncbi.nlm.nih.gov/pubmed/37460391
http://dx.doi.org/10.1093/bmb/ldad017