Mutant KRAS Mediates circARFGEF2 Biogenesis to Promote Lymphatic Metastasis of Pancreatic Ductal Adenocarcinoma

Circular RNAs (circRNA) contribute to cancer stemness, proliferation, and metastasis. The biogenesis of circRNAs can be impacted by the genetic landscape of tumors. Herein, we identified a novel circRNA, circARFGEF2 (hsa_circ_0060665), which was upregulated in KRAS(G12D) pancreatic ductal adenocarci...

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Detalles Bibliográficos
Autores principales: Kong, Yao, Luo, Yuming, Zheng, Shangyou, Yang, Jiabin, Zhang, Dingwen, Zhao, Yue, Zheng, Hanhao, An, Mingjie, Lin, Yan, Ai, Le, Diao, Xiayao, Lin, Qing, Chen, Changhao, Chen, Rufu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Cancer Metabolism and Molecular Mechanisms
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502454/
https://www.ncbi.nlm.nih.gov/pubmed/37363990
http://dx.doi.org/10.1158/0008-5472.CAN-22-3997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502454/
https://www.ncbi.nlm.nih.gov/pubmed/37363990
http://dx.doi.org/10.1158/0008-5472.CAN-22-3997

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