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Lorazepam Stimulates IL6 Production and Is Associated with Poor Survival Outcomes in Pancreatic Cancer

PURPOSE: This research investigates the association between benzodiazepines (BZD) and cancer patient survival outcomes, the pancreatic cancer tumor microenvironment, and cancer-associated fibroblast (CAF) signaling. EXPERIMENTAL DESIGN: Multivariate Cox regression modeling was used to retrospectivel...

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Detalles Bibliográficos
Autores principales: Cornwell, Abigail C., Tisdale, Arwen A., Venkat, Swati, Maraszek, Kathryn E., Alahmari, Abdulrahman A., George, Anthony, Attwood, Kristopher, George, Madison, Rempinski, Donald, Franco-Barraza, Janusz, Seshadri, Mukund, Parker, Mark D., Cortes Gomez, Eduardo, Fountzilas, Christos, Cukierman, Edna, Steele, Nina G., Feigin, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502465/
https://www.ncbi.nlm.nih.gov/pubmed/37587561
http://dx.doi.org/10.1158/1078-0432.CCR-23-0547