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Novel Histone Deacetylase 6 Inhibitor Confers Anti-inflammatory Effects and Enhances Gut Barrier Function

BACKGROUND/AIMS: The purpose of the current study was to examine the anti-inflammatory effects of CKD-506, a novel histone deacetylase 6 inhibitor, on human peripheral blood mononuclear cells (PBMCs) and CD4(+) T cells and to explore the relationship between CKD-506 and gut epithelial barrier functi...

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Detalles Bibliográficos
Autores principales: Lee, Jae-Young, Ma, Hyun Woo, Kim, Ji Hyung, Park, I Seul, Son, Mijeong, Ryu, Keun Ho, Shin, Jieun, Kim, Seung Won, Cheon, Jae Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Office of Gut and Liver 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502503/
https://www.ncbi.nlm.nih.gov/pubmed/36167345
http://dx.doi.org/10.5009/gnl220159