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ACA-28, an anticancer compound, induces Pap1 nuclear accumulation via ROS-dependent and -independent mechanisms in fission yeast

The nucleocytoplasmic transport of proteins is an important mechanism to control cell fate. Pap1 is a fission yeast nucleocytoplasmic shuttling transcription factor of which localization is redox regulated. The nuclear export factor Crm1/exportin negatively regulates Pap1 by exporting it from the nu...

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Detalles Bibliográficos
Autores principales: Takasaki, Teruaki, Obana, Reo, Fujiwara, Daiki, Tomimoto, Naofumi, Khandakar, Golam Iftakhar, Satoh, Ryosuke, Sugiura, Reiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502506/
https://www.ncbi.nlm.nih.gov/pubmed/37720683
http://dx.doi.org/10.17912/micropub.biology.000711