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Nestin overexpression reduces the sensitivity of gastric cancer cells to trastuzumab

BACKGROUND: Trastuzumab (TRA) shows significant efficacy in patients with human epidermal growth factor receptor 2 (HER2)-positive gastric cancer (GC). While TRA can help treat HER2-positive breast cancer, TRA resistance is a key clinical challenge. Nestin reportedly regulates the cellular redox hom...

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Detalles Bibliográficos
Autores principales: Wei, Yi-Chou, Zhu, Jiang-Yi, Wu, Jing, Yu, Shan, Li, Wei, Zhu, Meng-Xuan, Liu, Tian-Shu, Cui, Yue-Hong, Li, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502550/
https://www.ncbi.nlm.nih.gov/pubmed/37720426
http://dx.doi.org/10.21037/jgo-22-1048