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Guselkumab Modulates Differentially Expressed Genes in Blood of Patients With Psoriatic Arthritis: Results from Two Phase 3, Randomized, Placebo‐Controlled Trials

OBJECTIVE: To evaluate gene expression in blood of patients with psoriatic arthritis (PsA) versus healthy controls and identify changes associated with guselkumab treatment. METHODS: Whole blood transcriptome profiling via paired‐end RNA sequencing was conducted using samples from DISCOVER‐1 and DIS...

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Detalles Bibliográficos
Autores principales: Siebert, Stefan, Sweet, Kristen M., Ritchlin, Christopher T., Hsia, Elizabeth C., Kollmeier, Alexa P., Xu, Xie L., Seridi, Loqmane, Song, Qingxuan, Gao, Sheng, Chen, Warner, Miron, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502816/
https://www.ncbi.nlm.nih.gov/pubmed/37553909
http://dx.doi.org/10.1002/acr2.11589