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Hyper α2,6‐Sialylation Promotes CD4(+) T‐Cell Activation and Induces the Occurrence of Ulcerative Colitis

α2,6‐sialylation, catalyzed by α2,6‐sialyltransferase (ST6GAL1), plays a pivotal role in immune responses. However, the role of ST6GAL1 in the pathogenesis of ulcerative colitis (UC) remains unknown. ST6GAL1 mRNA is highly expressed in UC tissues compared with the corresponding adjacent normal tissu...

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Detalles Bibliográficos
Autores principales: Fan, Qingjie, Li, Mechou, Zhao, Weiwei, Zhang, Kaixin, Li, Ming, Li, Wenzhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502867/
https://www.ncbi.nlm.nih.gov/pubmed/37424034
http://dx.doi.org/10.1002/advs.202302607