MAVEN: compound mechanism of action analysis and visualisation using transcriptomics and compound structure data in R/Shiny

BACKGROUND: Understanding the Mechanism of Action (MoA) of a compound is an often challenging but equally crucial aspect of drug discovery that can help improve both its efficacy and safety. Computational methods to aid MoA elucidation usually either aim to predict direct drug targets, or attempt to...

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Detalles Bibliográficos
Autores principales: Hosseini-Gerami, Layla, Hernansaiz Ballesteros, Rosa, Liu, Anika, Broughton, Howard, Collier, David Andrew, Bender, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502988/
https://www.ncbi.nlm.nih.gov/pubmed/37715141
http://dx.doi.org/10.1186/s12859-023-05416-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502988/
https://www.ncbi.nlm.nih.gov/pubmed/37715141
http://dx.doi.org/10.1186/s12859-023-05416-8

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