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MAVEN: compound mechanism of action analysis and visualisation using transcriptomics and compound structure data in R/Shiny
BACKGROUND: Understanding the Mechanism of Action (MoA) of a compound is an often challenging but equally crucial aspect of drug discovery that can help improve both its efficacy and safety. Computational methods to aid MoA elucidation usually either aim to predict direct drug targets, or attempt to...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502988/ https://www.ncbi.nlm.nih.gov/pubmed/37715141 http://dx.doi.org/10.1186/s12859-023-05416-8 |