BAP1 mutations inhibit the NF-κB signaling pathway to induce an immunosuppressive microenvironment in uveal melanoma

BACKGROUND: Tumor immune microenvironment regulates the growth and metastasis of uveal melanoma (UM). This study aims to reveal the possible molecular mechanism of BRCA1-associated protein 1 (BAP1) mutations in affecting the tumor immune microenvironment in UM through mediating the nuclear factor-κB...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Wu, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503157/
https://www.ncbi.nlm.nih.gov/pubmed/37710185
http://dx.doi.org/10.1186/s10020-023-00713-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503157/
https://www.ncbi.nlm.nih.gov/pubmed/37710185
http://dx.doi.org/10.1186/s10020-023-00713-7

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