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Effect of Duvelisib, a Selective PI3K Inhibitor on Seizure Activity in Pentylenetetrazole-Induced Convulsions Animal Model

Epilepsy is one of the most common neurological diseases, which is caused by abnormal brain activity. A wide variety of studies have shown the importance of the phosphatidylinositol-3-kinase (PI3K) signaling pathway in epilepsy pathogenesis. Duvelisib (DUV) is a selective inhibitor of PI3K. The pres...

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Detalles Bibliográficos
Autores principales: Abdolrahmani, Mahnaz, Mirazi, Naser, Hosseini, Abdolkarim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503276/
https://www.ncbi.nlm.nih.gov/pubmed/37720697
http://dx.doi.org/10.1177/26331055231198013