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Drug repositioning of anti-microbial agent nifuratel to treat mast cell-mediated allergic responses

Objectives: Our objective was to assess the effects and mechanisms of nifuratel on IgE-mediated mast cell (MC) degranulation and anaphylaxis in both in vitro and in vivo settings. Methods: The anti-allergic activity of nifuratel was evaluated in mast cell cultures and the passive cutaneous anaphylax...

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Detalles Bibliográficos
Autores principales: Lee, Ji Eon, Choi, Min Yeong, Min, Keun Young, Jo, Min Geun, Kim, Young Mi, Kim, Hyuk Soon, Choi, Wahn Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503296/
https://www.ncbi.nlm.nih.gov/pubmed/37706235
http://dx.doi.org/10.1177/03946320231202349