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Differential regulation of the interferon response in systemic lupus erythematosus distinguishes patients of Asian ancestry

OBJECTIVES: Type I interferon (IFN) plays a role in the pathogenesis of systemic lupus erythematosus (SLE), but insufficient attention has been directed to the differences in IFN responses between ancestral populations. Here, we explored the expression of the interferon gene signatures (IGSs) in SLE...

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Detalles Bibliográficos
Autores principales: Rector, Ian, Owen, Katherine A, Bachali, Prathyusha, Hubbard, Erika, Yazdany, Jinoos, Dall'era, Maria, Grammer, Amrie C, Lipsky, Peter E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503349/
https://www.ncbi.nlm.nih.gov/pubmed/37709528
http://dx.doi.org/10.1136/rmdopen-2023-003475