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Luteolin peracetate and gossypolone inhibit immune complex-mediated neutrophil activation in vitro and dermal-epidermal separation in an ex vivo model of epidermolysis bullosa acquisita

INTRODUCTION: Natural products have been shown to an important source of therapeutics for human disease. In this study, we aimed to identify natural compounds as potential therapeutics for epidermolysis bullosa acquisita (EBA), an autoimmune disease caused by autoantibodies to type VII collagen (COL...

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Detalles Bibliográficos
Autores principales: Yang, Kai, Yin, Junping, Yue, Xiaoyang, Bieber, Katja, Riemekasten, Gabriela, Ludwig, Ralf J., Petersen, Frank, Yu, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503437/
https://www.ncbi.nlm.nih.gov/pubmed/37720234
http://dx.doi.org/10.3389/fimmu.2023.1196116