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KRAS/NRAS Mutations Associated with Distant Metastasis and BRAF/PIK3CA Mutations Associated with Poor Tumor Differentiation in Colorectal Cancer

BACKGROUND: The occurrence, progression, and prognosis of colorectal cancer (CRC) are regulated by EGFR-mediated signaling pathways. However, the relationship between the core genes (KRAS/NRAS/BRAF/PIK3CA) status in the signaling pathways and clinicopathological characteristics of CRC patients in Ha...

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Detalles Bibliográficos
Autores principales: Zeng, Juanzi, Fan, Wenwei, Li, Jiaquan, Wu, Guowu, Wu, Heming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503567/
https://www.ncbi.nlm.nih.gov/pubmed/37720173
http://dx.doi.org/10.2147/IJGM.S428580