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Adenosine A(2A) receptor blockade attenuates excitotoxicity in rat striatal medium spiny neurons during an ischemic-like insult

During brain ischemia, excitotoxicity and peri-infarct depolarization injuries occur and cause cerebral tissue damage. Indeed, anoxic depolarization, consisting of massive neuronal depolarization due to the loss of membrane ion gradients, occurs in vivo or in vitro during an energy failure. The neur...

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Detalles Bibliográficos
Autores principales: Coppi, Elisabetta, Cherchi, Federica, Gibb, Alasdair J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503621/
https://www.ncbi.nlm.nih.gov/pubmed/37488874
http://dx.doi.org/10.4103/1673-5374.375309