A multiplexed barcode approach to simultaneously evaluate gene delivery by adeno-associated virus capsid variants in nonhuman primates

BACKGROUND AND AIMS: Adeno-associated virus (AAV) vectors are widely used to deliver therapeutic transgenes to distinct tissues, including the liver. Vectors based on naturally occurring AAV serotypes as well as vectors using engineered capsids have shown variations in tissue tropism and level of tr...

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Detalles Bibliográficos
Autores principales: Stone, Daniel, Meumann, Nadja, Kuhlmann, Anne-Sophie, Peterson, Christopher W., Xie, Hong, Roychoudhury, Pavitra, Loprieno, Michelle A., Vu, Xuan-Khang, Strongin, Daniel E., Kenkel, Elizabeth J., Haick, Anoria, Stensland, Laurence, Obenza, Willimark M., Parrott, Jacob, Nelson, Veronica, Murnane, Robert D., Huang, Meei-Li, Aubert, Martine, Kiem, Hans-Peter, Büning, Hildegard, Jerome, Keith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503678/
https://www.ncbi.nlm.nih.gov/pubmed/37074875
http://dx.doi.org/10.1097/HC9.0000000000000009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503678/
https://www.ncbi.nlm.nih.gov/pubmed/37074875
http://dx.doi.org/10.1097/HC9.0000000000000009

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