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A TOX-ic axis of epigenetic stem cell maintenance and chemoresistance in colon cancer
Cancer stem cells drive tumor growth and survival via self-renewal and therapeutic resistance, but the upstream mechanisms are not well defined. In this issue of PLOS Biology, a study in colon cancer reveals a new signalling network that links epigenetic regulation to these phenotypes.
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503703/ https://www.ncbi.nlm.nih.gov/pubmed/37713380 http://dx.doi.org/10.1371/journal.pbio.3002295 |