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Role of succinyl substituents in the mannose-capping of lipoarabinomannan and control of inflammation in Mycobacterium tuberculosis infection

The covalent modification of bacterial (lipo)polysaccharides with discrete substituents may impact their biosynthesis, export and/or biological activity. Whether mycobacteria use a similar strategy to control the biogenesis of its cell envelope polysaccharides and modulate their interaction with the...

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Detalles Bibliográficos
Autores principales: Palčeková, Zuzana, Obregón-Henao, Andrés, De, Kavita, Walz, Amanda, Lam, Ha, Philp, Jamie, Angala, Shiva Kumar, Patterson, Johnathan, Pearce, Camron, Zuberogoitia, Sophie, Avanzi, Charlotte, Nigou, Jérôme, McNeil, Michael, Muñoz Gutiérrez, Juan F., Gilleron, Martine, Wheat, William H., Gonzalez-Juarrero, Mercedes, Jackson, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503756/
https://www.ncbi.nlm.nih.gov/pubmed/37669276
http://dx.doi.org/10.1371/journal.ppat.1011636