Hemolysis dictates monocyte differentiation via two distinct pathways in sickle cell disease vaso-occlusion

Sickle cell disease (SCD) is a hereditary hemoglobinopathy characterized by painful vaso-occlusive crises (VOC) and chronic hemolysis. The mononuclear phagocyte system is pivotal to SCD pathophysiology, but the mechanisms governing monocyte/macrophage differentiation remain unknown. This study exami...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yunfeng, Su, Shan, Shayo, Sarah, Bao, Weili, Pal, Mouli, Dou, Kai, Shi, Patricia A., Aygun, Banu, Campbell-Lee, Sally, Lobo, Cheryl A., Mendelson, Avital, An, Xiuli, Manwani, Deepa, Zhong, Hui, Yazdanbakhsh, Karina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503794/
https://www.ncbi.nlm.nih.gov/pubmed/37490346
http://dx.doi.org/10.1172/JCI172087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503794/
https://www.ncbi.nlm.nih.gov/pubmed/37490346
http://dx.doi.org/10.1172/JCI172087

Ejemplares similares