SMAD4 maintains the fluid shear stress set point to protect against arterial-venous malformations

Vascular networks form, remodel, and mature under the influence of both fluid shear stress (FSS) and soluble factors. Physiological FSS promotes and maintains vascular stability via synergy with bone morphogenic proteins 9 and 10 (BMP9 and BMP10). Conversely, mutation of the BMP receptors activin-li...

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Detalles Bibliográficos
Autores principales: Banerjee, Kuheli, Lin, Yanzhu, Gahn, Johannes, Cordero, Julio, Gupta, Purnima, Mohamed, Islam, Graupera, Mariona, Dobreva, Gergana, Schwartz, Martin A., Ola, Roxana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503796/
https://www.ncbi.nlm.nih.gov/pubmed/37490341
http://dx.doi.org/10.1172/JCI168352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503796/
https://www.ncbi.nlm.nih.gov/pubmed/37490341
http://dx.doi.org/10.1172/JCI168352

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