Pancreatic RECK inactivation promotes cancer formation, epithelial-mesenchymal transition, and metastasis

RECK is downregulated in various human cancers; however, how RECK inactivation affects carcinogenesis remains unclear. We addressed this issue in a pancreatic ductal adenocarcinoma (PDAC) mouse model and found that pancreatic Reck deletion dramatically augmented the spontaneous development of PDAC w...

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Detalles Bibliográficos
Autores principales: Masuda, Tomonori, Fukuda, Akihisa, Yamakawa, Go, Omatsu, Mayuki, Namikawa, Mio, Sono, Makoto, Fukunaga, Yuichi, Nagao, Munemasa, Araki, Osamu, Yoshikawa, Takaaki, Ogawa, Satoshi, Masuo, Kenji, Goto, Norihiro, Hiramatsu, Yukiko, Muta, Yu, Tsuda, Motoyuki, Maruno, Takahisa, Nakanishi, Yuki, Masui, Toshihiko, Hatano, Etsuro, Matsuzaki, Tomoko, Noda, Makoto, Seno, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503799/
https://www.ncbi.nlm.nih.gov/pubmed/37712427
http://dx.doi.org/10.1172/JCI161847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503799/
https://www.ncbi.nlm.nih.gov/pubmed/37712427
http://dx.doi.org/10.1172/JCI161847

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