Cell-free, high-density lipoprotein–specific phospholipid efflux assay predicts incident cardiovascular disease

BACKGROUND: Cellular cholesterol efflux capacity (CEC) is a better predictor of cardiovascular disease (CVD) events than HDL-cholesterol (HDL-C) but is not suitable as a routine clinical assay. METHODS: We developed an HDL-specific phospholipid efflux (HDL-SPE) assay to assess HDL functionality base...

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Detalles Bibliográficos
Autores principales: Sato, Masaki, Neufeld, Edward B., Playford, Martin P., Lei, Yu, Sorokin, Alexander V., Aponte, Angel M., Freeman, Lita A., Gordon, Scott M., Dey, Amit K., Jeiran, Kianoush, Hamasaki, Masato, Sampson, Maureen L., Shamburek, Robert D., Tang, Jingrong, Chen, Marcus Y., Kotani, Kazuhiko, Anderson, Josephine L.C., Dullaart, Robin P.F., Mehta, Nehal N., Tietge, Uwe J.F., Remaley, Alan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503808/
https://www.ncbi.nlm.nih.gov/pubmed/37471145
http://dx.doi.org/10.1172/JCI165370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503808/
https://www.ncbi.nlm.nih.gov/pubmed/37471145
http://dx.doi.org/10.1172/JCI165370

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