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Cell-free, high-density lipoprotein–specific phospholipid efflux assay predicts incident cardiovascular disease
BACKGROUND: Cellular cholesterol efflux capacity (CEC) is a better predictor of cardiovascular disease (CVD) events than HDL-cholesterol (HDL-C) but is not suitable as a routine clinical assay. METHODS: We developed an HDL-specific phospholipid efflux (HDL-SPE) assay to assess HDL functionality base...
Autores principales: | Sato, Masaki, Neufeld, Edward B., Playford, Martin P., Lei, Yu, Sorokin, Alexander V., Aponte, Angel M., Freeman, Lita A., Gordon, Scott M., Dey, Amit K., Jeiran, Kianoush, Hamasaki, Masato, Sampson, Maureen L., Shamburek, Robert D., Tang, Jingrong, Chen, Marcus Y., Kotani, Kazuhiko, Anderson, Josephine L.C., Dullaart, Robin P.F., Mehta, Nehal N., Tietge, Uwe J.F., Remaley, Alan T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503808/ https://www.ncbi.nlm.nih.gov/pubmed/37471145 http://dx.doi.org/10.1172/JCI165370 |
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