KRAB-zinc-finger proteins regulate endogenous retroviruses to sculpt germline transcriptomes and genome evolution

As transposable elements (TEs) coevolved with the host genome, the host genome exploited TEs as functional regulatory elements. What remains largely unknown are how the activity of TEs, namely, endogenous retroviruses (ERVs), are regulated and how TEs evolved in the germline. Here we show that KRAB...

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Detalles Bibliográficos
Autores principales: Otsuka, Kai, Sakashita, Akihiko, Maezawa, So, Schultz, Richard M., Namekawa, Satoshi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503828/
https://www.ncbi.nlm.nih.gov/pubmed/37720031
http://dx.doi.org/10.1101/2023.06.24.546405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503828/
https://www.ncbi.nlm.nih.gov/pubmed/37720031
http://dx.doi.org/10.1101/2023.06.24.546405

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