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KRAB-zinc-finger proteins regulate endogenous retroviruses to sculpt germline transcriptomes and genome evolution
As transposable elements (TEs) coevolved with the host genome, the host genome exploited TEs as functional regulatory elements. What remains largely unknown are how the activity of TEs, namely, endogenous retroviruses (ERVs), are regulated and how TEs evolved in the germline. Here we show that KRAB...
Autores principales: | Otsuka, Kai, Sakashita, Akihiko, Maezawa, So, Schultz, Richard M., Namekawa, Satoshi H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503828/ https://www.ncbi.nlm.nih.gov/pubmed/37720031 http://dx.doi.org/10.1101/2023.06.24.546405 |
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