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Temporal dynamics and genomic programming of plasma cell fates

Affinity-matured plasma cells (PCs) of varying lifespans are generated through a germinal center (GC) response. The developmental dynamics and genomic programs of antigen-specific PC precursors remain to be elucidated. Using a model antigen, we demonstrate biphasic generation of PC precursors, with...

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Detalles Bibliográficos
Autores principales: Vijay, Godhev Kumar Manakkat, Zhou, Ming, Thakkar, Kairavee, Rothrauff, Abigail, Chawla, Amanpreet Singh, Chen, Dianyu, Lau, Louis Chi-Wai, Habib, Peter, Chetal, Kashish, Chhibbar, Prabal, Fan, Jingyu, Das, Jishnu, Joglekar, Alok, Borghesi, Lisa, Salomonis, Nathan, Xu, Heping, Singh, Harinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503833/
https://www.ncbi.nlm.nih.gov/pubmed/37720050
http://dx.doi.org/10.21203/rs.3.rs-3296446/v1