Mechanisms of mRNA processing defects in inherited THOC6 intellectual disability syndrome

THOC6 is the genetic basis of autosomal recessive THOC6 Intellectual Disability Syndrome (TIDS). THOC6 facilitates the formation of the Transcription Export complex (TREX) tetramer, composed of four THO monomers. The TREX tetramer supports mammalian mRNA processing that is distinct from yeast TREX d...

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Detalles Bibliográficos
Autores principales: Werren, Elizabeth, LaForce, Geneva, Srivastava, Anshika, Perillo, Delia, Johnson, Katherine, Berger, Brandon, Regan, Samantha, Pfennig, Christian, Baris, Safa, de Munnik, Sonja, Pfundt, Rolph, Hebbar, Malavika, Jimenez Heredia, Raul, Karakoc-Aydiner, Elif, Ozen, Ahmet, Dmytrus, Jasmin, Krolo, Ana, Corning, Ken, Prijoles, Eloise, Louie, Raymond, Lebel, Robert, Le, Thuy-Linh, Amiel, Jeanne, Gordon, Christopher, Boztug, Kaan, Girisha, Katta, Shukla, Anju, Bielas, Stephanie, Schaffer, Ashleigh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503840/
https://www.ncbi.nlm.nih.gov/pubmed/37720017
http://dx.doi.org/10.21203/rs.3.rs-2126145/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503840/
https://www.ncbi.nlm.nih.gov/pubmed/37720017
http://dx.doi.org/10.21203/rs.3.rs-2126145/v1

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