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CSF1R inhibition is not specific to innate immune cells but also affects T-helper cell differentiation independently of microglia depletion

Colony-stimulating factor 1 receptor (CSF1R) inhibition has been proposed as a specific method for microglia depletion. However, recent work revealed that in addition to microglia, CSF1R inhibition also affects other innate immune cells, such as peripheral monocytes and tissue-resident macrophages o...

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Detalles Bibliográficos
Autores principales: Lei, Fengyang, Cui, Naiwen, Zhou, Chengxin, Chodosh, James, Vavvas, Demetrios G., Paschalis, Eleftherios I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503844/
https://www.ncbi.nlm.nih.gov/pubmed/37720036
http://dx.doi.org/10.21203/rs.3.rs-3308220/v1