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CSF1R inhibition is not specific to innate immune cells but also affects T-helper cell differentiation independently of microglia depletion
Colony-stimulating factor 1 receptor (CSF1R) inhibition has been proposed as a specific method for microglia depletion. However, recent work revealed that in addition to microglia, CSF1R inhibition also affects other innate immune cells, such as peripheral monocytes and tissue-resident macrophages o...
Autores principales: | Lei, Fengyang, Cui, Naiwen, Zhou, Chengxin, Chodosh, James, Vavvas, Demetrios G., Paschalis, Eleftherios I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503844/ https://www.ncbi.nlm.nih.gov/pubmed/37720036 http://dx.doi.org/10.21203/rs.3.rs-3308220/v1 |
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