The PML1-WDR5 axis regulates H3K4me3 marks and promotes stemness of estrogen receptor-positive breast cancer

The alternative splicing of PML precursor mRNA gives rise to various PML isoforms, yet their expression profile in breast cancer cells remains uncharted. We discovered that PML1 is the most abundant isoform in all breast cancer subtypes, and its expression is associated with unfavorable prognosis in...

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Detalles Bibliográficos
Autores principales: Kao, Hung-Ying, Pai, Chun-Peng, Wang, Han, Agarwal, Neel, Adams, Joshua, Liu, Zhenghao, Seachrist, Darcie, Keri, Ruth, Schiemann, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503857/
https://www.ncbi.nlm.nih.gov/pubmed/37720048
http://dx.doi.org/10.21203/rs.3.rs-3266720/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503857/
https://www.ncbi.nlm.nih.gov/pubmed/37720048
http://dx.doi.org/10.21203/rs.3.rs-3266720/v1

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