Whole-body modelling reveals microbiome and genomic interactions on reduced urine formate levels in Alzheimer’s disease

In this study, we aimed to understand the potential role of the gut microbiome in the development of Alzheimer's disease (AD). We took a multi-faceted approach to investigate this relationship. Urine metabolomics were examined in individuals with AD and controls, revealing decreased formate and...

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Detalles Bibliográficos
Autores principales: Martinelli, Filippo, Heinken, Almut, Henning, Ann-Kristin, Wörheide, Maria A., Hensen, Tim, González, Antonio, Arnold, Matthias, Asthana, Sanjay, Budde, Kathrin, Engelman, Corinne D., Estaki, Mehrbod, Grabe, Hans-Jörgen, Heston, Margo, Johnson, Sterling, Kastenmüller, Gabi, Martino, Cameron, McDonald, Daniel, Rey, Federico, Kilimann, Ingo, Peters, Olive, Wang, Xiao, Spruth, Eike Jakob, Schneider, Anja, Fliessbach, Klaus, Wiltfang, Jens, Hansen, Niels, Glanz, Wenzel, Buerger, Katharina, Janowitz, Daniel, Laske, Christoph, Munk, Matthias H., Spottke, Annika, Roy, Nina, Nauck, Matthias, Teipel, Stefan, Knight, Rob, Kaddurah-Daouk, Rima, Bendlin, Barbara B., Hertel, Johannes, Thiele, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503865/
https://www.ncbi.nlm.nih.gov/pubmed/37720019
http://dx.doi.org/10.21203/rs.3.rs-3306891/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503865/
https://www.ncbi.nlm.nih.gov/pubmed/37720019
http://dx.doi.org/10.21203/rs.3.rs-3306891/v1

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