De Novo Human Angiotensin-Converting Enzyme 2 Decoy NL-CVX1 Protects Mice From Severe Disease After Severe Acute Respiratory Syndrome Coronavirus 2 Infection

The emergence of novel variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) underscores the need to investigate alternative approaches to prevent infection and treat patients with coronavirus disease 2019. Here, we report the preclinical efficacy of NL-CVX1, a de novo decoy that...

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Detalles Bibliográficos
Autores principales: Rebelo, Maria, Tang, Cong, Coelho, Ana R, Labão-Almeida, Carlos, Schneider, Matthias M, Tatalick, Laurie, Ruivo, Pedro, de Miranda, Marta Pires, Gomes, Andreia, Carvalho, Tânia, Walker, Matthew J, Ausserwoeger, Hannes, Pedro Simas, J, Veldhoen, Marc, Knowles, Tuomas P J, Silva, Daniel-Adriano, Shoultz, David, Bernardes, Gonçalo J L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503951/
https://www.ncbi.nlm.nih.gov/pubmed/37279654
http://dx.doi.org/10.1093/infdis/jiad135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503951/
https://www.ncbi.nlm.nih.gov/pubmed/37279654
http://dx.doi.org/10.1093/infdis/jiad135

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