A drug repurposing screen for whipworms informed by comparative genomics

Hundreds of millions of people worldwide are infected with the whipworm Trichuris trichiura. Novel treatments are urgently needed as current drugs, such as albendazole, have relatively low efficacy. We have investigated whether drugs approved for other human diseases could be repurposed as novel ant...

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Detalles Bibliográficos
Autores principales: Coghlan, Avril, Partridge, Frederick A., Duque-Correa, María Adelaida, Rinaldi, Gabriel, Clare, Simon, Seymour, Lisa, Brandt, Cordelia, Mkandawire, Tapoka T., McCarthy, Catherine, Holroyd, Nancy, Nick, Marina, Brown, Anwen E., Tonitiwong, Sirapat, Sattelle, David B., Berriman, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503962/
https://www.ncbi.nlm.nih.gov/pubmed/37669291
http://dx.doi.org/10.1371/journal.pntd.0011205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503962/
https://www.ncbi.nlm.nih.gov/pubmed/37669291
http://dx.doi.org/10.1371/journal.pntd.0011205

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